Regulation of toxin–antitoxin systems by proteolysis
نویسندگان
چکیده
منابع مشابه
Regulation by proteolysis: developmental switches.
The energy-dependent proteases originally defined in Escherichia coli have proven to have particularly important roles in bacterial developmental systems, including sporulation in Bacillus subtilis and cell cycle in Caulobacter. Degradation of key regulatory proteins participates, with regulation of synthesis and activity of the regulators, to ensure tight control and, where required, irreversi...
متن کاملRegulation of transcription factor function by proteolysis.
67 Kyriakis, J. M. et al. (1996) Nature (London) 380, 75-79 Zanke, B. W., Boudreau, K., Rubie, E., Winnett, E., Tibbles, L. A., Zon, L., Kyriakis, J., Liu, F. F. and Woodgett, J. R. (1996) Curr. Biol. 6, 606-613 McCarthy, S. A., Samuels, M. L., Pritchard, C. A., Abraham, J. A. and McMahon, M. (1995) Genes Dev. 9, 1953-1964 68 Nishima, H., Fischer, K. D., Radvanyi, L., Shahinian, A., Hakem, R., ...
متن کاملRegulation of transcription factor latency by receptor-activated proteolysis.
The transcription factor Stp1 is endoproteolytically processed in response to extracellular amino acids by the plasma membrane SPS (Ssy1-Ptr3-Ssy5)-sensor. Processed Stp1, lacking a cytoplasmic retention motif, enters the nucleus and induces amino acid transporter gene expression. The SPS-sensor component Ssy5 is a chymotrypsin-like protease with a Pro-domain and a catalytic domain. The Pro-dom...
متن کاملNovel mechanisms for enzymatic regulation of phosphatidylcholine synthesis by proteolysis
Pulmonary surfactant is a critical surface-active substance consisting of dipalmitoylphosphatidylcholine (DPPtdCho) and key apoproteins that are produced and secreted into the airspace from alveolar type II epithelial cells. Surfactant deficiency leads to severe lung atelectasis, ventilatory impairment, and gas-exchange abnormalities. These are features of the acute lung injury syndrome, charac...
متن کاملCi Proteolysis: Regulation by a Constellation of Phosphorylation Sites
Proteolytic processing of Ci requires phosphorylation by the kinases Sgg/GSK3 and CK1. The newly identified phosphorylation sites form clusters with previously described PKA sites in which phosphorylation by PKA acts to prime subsequent phosphorylation by Sgg/GSK3 and CK1.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Plasmid
سال: 2013
ISSN: 0147-619X
DOI: 10.1016/j.plasmid.2013.01.007